COMPARISON OF LIPID PROFILE AND APOPROTEIN IN SEDENTARY WORKERS AND THOSE INVOLVED IN REGULAR EXERCISE

Authors

  • Abdus Salam Khan Gandapur
  • Modoodul Manan
  • Modoodul Manan
  • Ghazala Nazir
  • Naeen Uzma
  • Javaid Akhtar Chawla
  • Azhar Jadoon
  • Asya Tauqeer

Abstract

Background: One of the important effects of exercise on human body is on the metabolic systemespecially on lipids; elevated lipids and lipoprotein are risk factors for coronary heart disease. Thiscase-control study was conducted t o compare the lipid profile and apo-protein B levels insedentary workers and subjects involved in regular exercise. Methodology: The study wasconducted at Women Medical College Abbottabad, from July 2004 to January 2005. Subjectswere civilians and army men involved in regular exercise for more than 6 months duration (testgroup) and sedentary workers (control group). The age, body weight, height, waist hip ratio andother related findings were recorded on a special proforma. Fasting blood samples were taken andwere analyzed for lipid profile and apoprotein B levels. Statistical analysis was done by the Chisquare and the S tudent t tests and level of significance was recorded. Result: The subjectscomprised 29 army men, 24 civilians and 39 sedentary workers. Significant differences werefound between the control and test groups for WHR, total cholesterol, HDL, LDL, Triglycerides,Apo B, and Cholesterol/HDL ratio; in addition the civilian group also showed significantdifferences from the control group in BMI values. Although LDL levels were lower in army thansedentary group, the difference was statistically nonsignificant. Significant differences were foundbetween the army and civilian groups in age, HDL, Triglycerides and Apo B values. Conclusion:Long term aerobic exercise has beneficial effects in decreasing Apo- protein B levels, LDL levelsand total cholesterol /HDL ratio. Exercise habits should be encouraged in general population todecrease the cardiovascular disease risk.Key Words: Exercise, lipid profile, apo-lipoprotein B.

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