• Shahzad Najeeb
  • Azhar Munir Qureshi
  • Anis -ur- Rehman
  • Fayaz Ahmad
  • Sher Shah
  • Asfand Yar Khan
  • Tahir Saeed Siddiqui


Background: Neonatal seizures (NS) affect approximately 1% of neonates. Clonic, tonic, myoclonicand subtle seizures are the common types. Birth asphyxia, sepsis, metabolic derangements, intracranialbleed, kernicterus, tetanus and 5th day fits are the common aetiologies. This study was planned toevaluate the types and causes of neonatal seizures. Methods: It was a descriptive case series conductedat Ayub Teaching Hospital, Abbottabad from 12th December 2006 to 25th September 2007 on neonateshaving seizures. Serum chemistry, blood counts, cerebrospinal fluid examination and cranial ultrasoundwere done in all patients. Blood culture, renal and liver function tests, computerised tomography scan,metabolic and septic screening was done in selected patients. Descriptive statistics were applied foranalysis. Results: Tonic clonic seizure was the commonest type (28%) followed by multi-focal clonic,and focal tonic seizures (25% each). Birth asphyxia was found to be the main aetiology (46%).Conclusion: Tonic clonic seizure was the commonest type and birth asphyxia the main aetiologyidentified in the majority of neonatal seizures.Keywords: Neonatal seizures, Aetiology, Seizures, Epilepsy, Neonates


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