EARLY VERSUS LATE ARTERIO-VENOUS FISTULAE: IMPACT ON FAILURE RATE
Abstract
Background: Haemodialysis is the primary mode of renal replacement therapy for patients of endstage renal disease. The most important determinant for effective haemodialysis is a reliable vascularaccess. Arterio-venous (AV) fistula is the closest to be an ideal long-term haemodialysis vascularaccess. The creation of fistulas or grafts is recommended before starting haemodialysis, this study wasundertaken to determine the impact of timing of AV fistula creation on its failure rate. Methods: It is adescriptive study. All patients with chronic kidney disease (CKD) reporting to Armed Forces Instituteof Urology (AFIU) and Military Hospital (MH) Rawalpindi from January 2008 to October 2009 inwhom vascular access was created were included. The patients were followed prospectively and acomplete data about their haemodialysis and vascular access was maintained. Results: A total of 168permanent accesses were created in 112 patients in this study. The mean duration of follow-up was14.05±4.45 months. Early access creation group included 23 patients and late access creation groupincluded 89 patients. Out of 168 fistulas that were created, 54 fistulas failed with 45 (83.3%) of thesefrom patients of late access creation group. Age, gender and diabetes mellitus (DM) had no significantaffect on failure rate of fistulas. Conclusion: Timely referral to nephrologists and early creation ofpermanent vascular access by dedicated team work can improve the success rate of AV fistulae soenhancing quality of life of patients of end stage renal disease.Keywords: Nephrology consultation, Haemodialysis, Arterio-venous fistulaReferences
Kinchen KS, Sadler J, Fink N, Brookmeyer R, Klag MJ, Levey
AS, et al. The timing of specialist evaluation in chronic kidney
disease and mortality. Ann Intern Med 2002;137:479–86.
Arora P, Obrador GT, Ruthazer R, Kausz AT, Meyer KB,
Jenuleson CS, et al. Prevalence, predictors and consequences of
late nephrology referral at a tertiary care center. J Am Soc
Nephrol 1999;10:1281–6.
Schmidt RJ, Domico JR, Sorkin MI, Hobbs G. Early referral and
its impact on emergent first dialyses, health care costs, and
outcome. Am J Kidney Dis 1998;32:278–83.
Ifudu O, Dawood M, Iofel Y, Valcourt JS, Friedman EA.
Delayed referral of black, Hispanic, and older patients with
chronic renal failure. Am J Kidney Dis 1999;33:728–33.
Jungers P, Massy ZA, Khoa NT, Choukroun G, Robino C,
Fakhouri F, et al. Longer duration of predialysis nephrological
care is associated with improved long-term survival of dialysis
patients. Nephrol Dial Transplant 2001;16:2357–64.
Stack AG. Impact of timing of nephrology referral and preESRD care on mortality risk among new ESRD patients in the
United States. Am J Kidney Dis 2003;41:505–7.
NKF-K/DOQI Clinical Practice Guidelines for Vascular Access:
Update 2000. Am J Kidney Dis 2001;37:S137–81.
Reddan D, Klassen P, Frankenfield DL, Szczech L, Schwab S,
Coladonato J, et al. National profile of practice patterns for
hemodialysis vascular access in the United States. J Am Soc
Nephrol 2002;13;2117–24.
Pisoni RL, Young EW, Dykstra DM, Greenwood RN, Hecking
E, Gillespie B, et al. Vascular access use in Europe and the
United States: Results from the DOPPS. Kidney Int
;61:305–16.
Hoen B, Dauphin PA, Hestin D, Kessler M. EPIBACDIAL: a
multicenter prospective study of risk factors for bacteremia in
chronic hemodialysis patients. J Am Soc Nephrol 1998;9:869–76.
Powe NR, Jaar B, Furth SL, Hermann J, Briggs W. Septicemia in
dialysis patients: incidence, risk factors, and prognosis. Kidney
Int 1999;55:1081–90.
Anees M, Mumtaz A, Nazir M, Ibrahim M, Rizwan SM, Kausar
T. Referral pattern of hemodialysis patients to nephrologists. J
Coll Phys Surg Pak 2007;17:671–4.
Ethier J, Mendelssohn DC, Elder SJ, Hasegawa T, Akizawa T,
Akiba T, et al. Vascular access use and outcomes: an
international perspective from the dialysis outcomes and practice
patterns study. Nephrol Dial Transplant 2008;23:3219–26.
Published
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.