EFFECTS OF INTENSITY AND DURATION OF EXERCISE ON TOTAL LEUKOCYTE COUNT IN NORMAL SUBJECTS
AbstractBackground: Leucocytes the mobile units of the protective system of the body, may circulate freely in the blood, adhere to the vascular endothelium in sites where blood flow is relatively slow and then once again re-enter the circulation in a process of continuous exchange. This process of continuous exchange of leucocytes is influenced by proper stimulation such as exercise. This study was done to observe the effects of intensity and duration of exercise on total leucocyte count. Methods: Two groups of normal healthy male adult subjects were exercised on treadmill. Group-I performed exercise by running for a duration of 2-3 minutes, at 7% grade (4 degree inclination) and at constant speed ranging from 7.5 to 9 Km/hour while group-II walked on treadmill for a duration of 7-10 minutes at zero grade and at constant speed ranging from 5 to 6 Km/hour. Blood sample was drawn before exercise, immediately after exercise and after 30 minutes of rest after the exercise. Total leukocyte count was then done by improved Neubauer haemocytometer. Results: The mean of pre-exercise total leucocyte count of Group-I subjects (n=15) was 9750 ± 384.47/µl, while immediately after exercise the mean total leucocyte count increased to 17856.66 ± 1213.24/µl and after 30 minutes rest, it came down to 10396.67 ± 648.35/µl. Whereas, the mean of total leucocyte count of group-II subjects (n=15) was 10266.66 ± 307.60/µl pre-exercise, 16336.66 ± 866.30/µl immediately post-exercise and 1162.33 ± 718.85/µl at 30 minutes post-exercise. The total leucocyte count increased significantly immediately after exercise and it significantly decreased after 30 minutes of rest but was still higher than the pre-exercise count in both the groups Conclusion: It is clearly reflected by this study that the magnitude of exercise-induced leucocytosis is higher in exercise of more intensity and less duration.
Oldridge NB, Guyatt GH, Fischer ME, Rimm AA. Cardiac rehabilitation after myocardial infarction. JAMA 1988; 260: 945-950.
Boas SR, Joswiak ML, Nixon PA, Kurland G, O’Connor M.J, Bufalino K et al. Effects of anaerobic exercise on the immune system in eight to seventeen year old trained and untrained boys. J Pediatrics 1996; 129: 846-855.
Guyton A.C. and Hall J.E. Textbook of Medical Physiology, W.B. Saunders, Philadelphia, 10th Edn., 2000; p.392.
Shek PN, Sabiston BH, Buguet A, Radomski M.W. Strenuous exercise and immunological changes: A multiple point analysis of leucocytes subsets, CD4/CD8 ratio, immunoglobulin production and NK cell response. Int J Sports Med 1995; 16(7): 466-474.
Kayashima S, Ohno H, Fujioka T, Taniguchi N, Nugata N. Leucocytosis as a marker of organ damage induced by chronic strenuous physical exercise. Eur J Appl Physiol 1995; 70 (5): 413-420.
McCarthy DA, Perry JD, Dale MM. Leucocytosis induced by exercise. Br Med J 1987; 295: 636.
Moyna NM, Acker GR, Weber KM, Fulton JR, Goss FL, Robertson RS, et al. The effects of incremental submaximal exercise on circulating leucocytes in physically active and sedentary males and females. Eur J Applied Physiol 1996; 74(3): 211-218.
Iversen PO, Arvesen BL, Benestad HB. No mandatory role for the spleen in the exercise induced leucocytosis in man. Clin Sci 1994; 86: 505-510.
Gabriel H, Kindermann W. The acute immune response to exercise: What does it mean? Int J Sports Med 1997; 18 (Suppl. 1): S 28-45.
Nieman DC, Cannarella NSL, Donohue KM, Chritton DB, Haddock BL., Stout RW et al. The effects of acute moderate exercise on leucocyte and lymphocyte subpopulations. Med Sci Sports Exercise 1991; 23(5): 578-585.
Suzuki K, Naganuma S, Totruka M, Suzuki KJ, Mochizuki M, Shiraishi M, et al. Effects of exhaustive endurance exercise and its one week daily repetition on neutrophil count and functional status in untrained men. Int J Sports Med 1996; 17(3): 205-212.
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.