REFERENCE HAEMATOLOGICAL VALUES FOR FULL TERM HEALTHY NEWBORNS FROM RURAL SINDH, PAKISTAN
Abstract
Background: Normal values of complete blood counts show variation from region to region and between different ethnic groups. It is important to establish reference range for these values in our population for clinical use by our physicians. This descriptive cross sectional study aimed at establishing the normal reference values of complete blood counts in physically normal full term new-borns of Panu Aqil, Rural Sind, Pakistan. Methods: The study was conducted at Combined Military Hospital, Panu Aqil Cantonment, from January 2010 to March 2011, on 316 term normal neonates selected on the basis of gestational age of 37 weeks or more with uneventful antenatal period. During the initial 12 hours of delivery, 2 ml Cord blood was collected in bottle containing tripotassium ethylene diamine tetra acetic acid (K3EDTA) as the anticoagulant and Complete blood counts were performed by Sysmex KX-21 automated haematology analyser. Blood films were prepared and stained by Leishman stain. Results: The haemoglobin was mean±SD 15.4±1.9 g/dL. The Mean Corpuscular Volume (MCV) was 103.4±4.6 fL, while Mean Corpuscular haemoglobin (MCH) was 33.8±1.6 pg. The Red cell Distribution Width-CV (RDW-CV) was 18.5±1.8%. The total leukocyte count (TLC) was mean±SD 13.7±4.0x109 /L. The Absolute Neutrophil count (ANC) was mean±SD 7.7±3.0x109 /L. The Absolute Lymphocyte count (ALC) was mean±SD 5.1±1.8x109 /L. Platelet count was mean±SD 285±62x109 /L. Conclusion: Our values provide reference range for haematological values in healthy newborns of Panu Aqil, Rural Sindh, for clinical use by our physicians.Keywords: Healthy new-borns, haematological, reference values, Rural SindhReferences
Mukiibi JM, Nkrumah FK, Kaur M, Pollard R, Akino V, Nhembe M. Neonatal hematology in Zimbabwe-II. The red cell and white cell parameters. Cent Afr J Medi 1995;41(3):76–82.
Stancheva VP, Sherman GG, Avent M, Cory BJ, Ballot DE, Cooper PA, et al. Hematological reference ranges in black very low birth weight infants. Pediatr Hematol Oncol 2002;19(2):91–4.
Solberg HE. Establishment and use of reference values. In: Burtis CA, Ashwood ER, eds. Tietz textbook of clinical chemistry, 4th ed. St. Louis: Saunders, 2006:425–48.
McElory PD, Lal AA, Hawley WA, Bloland PB, Kulie FO, Oloo AJ, et al. Analysis of repeated hemoglobin measures in full term, normal birth weight Kenyan children between birth and four years of age III. The asembo bay cohort project. Am J Trop Med Hyg 1999;61(6):932–40.
National Reconstruction Bureau site. Tehsils & Unions in the District of Sukkur (Online). (Cited 10 March 2013). Available from URL: http://www.nrb.gov.pk/lg_election/union.asp?district=43&dn=Sukkur.
Jokhio AH, Winters HR, Cheng KK. An intervention involving traditional birth attendants and peri natal and maternal mortality in Pakistan. N Eng J Med 2005;352(20):2091–9.
Fatmi Z, Avan BI. Demographic, socio-economic and environmental determinants of utilisation of antenatal care in a rural setting of Sindh, Pakistan. J Pak Med Assoc 2002;52(4):138–42.
Development Statistics of Sind 2011. Bureau of Statistics, Planning and Development Department, Government of Sind Karachi 75000.
Shaikh BT, Hatcher J. Health seeking behaviour and health service utilization in Pakistan: challenging the policy makers. J Public Health (Oxf) 2005;27(1):49–54.
Husain N, Creed F, Tomenson B. Depression and social stress in Pakistan. Psychol Med 2000;30(2):395–402.
Zahidie A, Kazi A, Fatmi Z, Bhatti M T, Dureshawar S. Social environment and depression pregnant women in rural areas of Sind, Pakistan. J Pak Med Assoc 2011;61(12):1183–9.
Agha A, White F, Younus M, Kadir MM, Ali S, Fatmi Z. Eight key household practices of Integrated Management of Childhood Illnesses (IMCI) amongst mothers of children aged 6 to 59 months in Gambat, Sindh, Pakistan. J PakMed Assoc 2007;57(6):288–93.
Matoth Y, Zaizov R, Varsano I. Postnatal changes in some red cell parameters. Acta Paediatr Scand 1971;60(3):317–23.
Tauseef K, Ali N, Ahmed S, Zafar H, Anwar J. Variation in reference values of haematological parameters between Regional and International Literature amongst the neonates. Isra Med J 2011; 3(1): 20–4.
Maconi M, Rolfo A, Cardropoli S, Brini M, Danise P. Hematological values in healthy and small for gestational age newborns. Lab Hematol 2005;11(2):152–6.
Mukiibi JM, Mtimavalye LA, Broadhead R, Mzula E, Dzinyemba WE, Merrick R, et al. Some hematological parameters in Malawian neonates. East Afri Med J 1995;72(1):10–4.
Published
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
