• Muhammad Arif
  • Zafar Iqbal
  • Zia -ul- Islam


Objective: The purpose of this study was to evaluate the frequency of metastatic retinoblastoma oninitial presentation. Design: Prospective study. Place and duration of study: Supra Regional Centrefor Retinoblastoma, Department of Ophthalmology, Khyber Teaching Hospital Peshawar Pakistanfrom 1st July 1999 to 31st January 2003. Methods: Data was collected from 80 registeredRetinoblastoma patients admitted and examined under anaesthesia for tumours assessment. Diagnosiswas supported with the help of CT scan and confirmed by histopathology of the enucleated specimenfor evidence of optic nerve invasion by the tumour. Results: Twenty (25%) patients were presenting asMetastasis on initial presentation. Mean age was 3.5 years, range was 7 months to 12 years. Out ofthese 20 patients with metastasis, 10 were male and 10 were female. Eighteen (90%) of them were fromlower socio-economic group. Conclusion: Failure in early diagnosis of retinoblastoma, advance ageand unilateral disease are associated with extraocular spread; this tragic scenario can be prevented bestbe early detection and prompt treatment plan implementation.Keywords: CT Scan, Optic nerve invasion, Orbital and Lymph node metastasis.


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