ROLE OF SURGICAL APPROACHES: INFLUENCING TUMOUR RECURRENCE IN NASOPHARYNGEAL ANGIOFIBROMA

Authors

  • Raza Muhammad Department of ENT, Ayub Teaching Hospital Abbottabad
  • Altaf Hussain Pakistan Institute of Medical Sciences, Islamabad
  • Fazal Rehman Hayatabad Medical Complex, Peshawar
  • Johar Iqbal Hayatabad Medical Complex, Peshawar
  • Munib Khan Hayatabad Medical Complex, Peshawar
  • Gohar Ullah Hayatabad Medical Complex, Peshawar
  • Zakir Khan Department of ENT, Ayub Teaching Hospital Abbottabad

Abstract

Background:  Juvenile nasopharyngeal angiofibroma (JNA) is an uncommon tumour constituting less than 1% of all head & neck tumours. This tumour has an aggressive local behaviour if left untreated. Surgery is the mainstay of treatmentwith no common consensus on a single approach. Tumour stage and surgical approaches are the major determinants of outcome. The objective of this study was to evaluate the influence of surgical approaches on tumour recurrence in patients with nasopharyngeal angiofibroma. Methods: This descriptive study was conducted in the Department of ENT and Head and Neck Surgery, PIMS, Islamabad and Ayub Medical Institution, Abbottabad from Jan 2010 to Jan 2014 consisting of 34 diagnosed cases of nasopharyngeal angiofibroma. All patients were treated surgically while radiotherapy was given in a few. All patients were followed up for one year. Results: Among 34 patients, 25 were treated by lateral rhinotomy approach with medial maxillectomy, 5 by mid-facial degloving approach and 3 by transpalatine approach. One patient with cavernous sinus involvement was treated by radiotherapy. Patients were followed up for one year both by clinical examination and imaging if needed. Recurrence was found in 15% (5/33) patients and postop radiotherapy was given to them. Conclusion: Lateral rhinotomy approach with medial maxillectomy is highly effective even in advanced stage JNA for complete removal of the disease. Postoperative radiotherapy is an effective adjuvant.Keywords: Juvenile nasopharyngeal angiofibroma, Lateral rhinotomy, recurrence

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Published

2015-06-20

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