CHANGING PROFILE OF ENTERIC FEVER IN CHILDREN
AbstractA total of 300 cases of PUO (Pyrexia of Unknown Origin) were admitted to the Paediatrics Unit ofWomen and Children Hospital, Abbottabad during one year (June 1994 - May, 1995). They were examinedfor their detailed clinical profile. About 2/3rd of them had fever as their presenting symptom. Otherassociated predominant features were dizziness-51 (30%), anorexia-48 (28%), loose motions-47 (27.6%),cough-38 (22.4%}), headache-25 (14.7%), coated tongue-21 2(12.4%.), & jaundice-5 (2.9%). 80%, patientswere admitted when complications had developed, such as gastroenteritis-68 (40%), enteric encephalopathy-65 (38.2%), drug toxicity-30 (17.6%), peritonitis-25 (14.7%), cholecystitis-18 (10.6%), myocarditis-6(3.5%), and ataxia-2 (1.2%).In the first 9 months, response to chloramphenicol was very good but this changed to resistance andin the last 3 months most of the cases were resistant to chloramphenicol treatment.
Kumar, Cotran and Robbins. The Gastrointestinal tract.
Basic Pathology. Philadelphia, WB Saunders, 1992, 505.
Nagi AH, et al. An analysis of Typhoid-A clinical
profile. Biomedical, Pak. Biomedical Res. Society,
Vol.,8 Jan-June, 1992.
Sharma A & Gothwala G. Clinical profile and outcome
in enteric fever. Indian Paediatr. 1993, Jan; 30(1): 47-50.
Rao PS, Rajashekar V, Varghese GK, & Shivanadda PG.
Emergence of multidrug-resistant Salmonella typlii in
rural southern India. Am. J. Trop. Med. Hyg. 1993 Jan;
Haider KK, Dalai BSI, Ghose E, Sanyal S.
Chloramphenicol resistant Salmonella typhi: the cause
of recent outbreak of enteric fever in Calcutta. Indian. J.
Pathol. Microbiol. 1992 Jan; 35(1): 11-17.
Montasser MF, Ibrahim FH, & Abdel Wahab MF. Fatal
complications of acute enteric fevers. J. Egypt. Public.
Health. Assoc. 1991, 66(5-6): 545-56.