• Jamila Farid
  • Taher Salim
  • Javed Sarwar
  • Muhammad Idris
  • Nasreen Gul
  • Syed Humayun Shah
  • Muhammad Suleman


Background: Hepatitis B is inflammation of the liver caused by a Hepatitis B virus, having aparenteral mode of entry and infecting millions of people around the world. Objective: Thepresent study was planned to assess the seroprevalence of Hepatitis B in women of reproductiveage in Hazara in order to promote disease prevention in the perinatal period by vaccination againstHepatitis B. Subjects and Methods: Women 15–45 years old belonging to Hazara Division wereincluded in this descriptive, cross-sectional study conducted over a period of one year at theDepartment of Microbiology, Ayub Medical College, Abbottabad in collaboration with theDepartment of Pathology, Ayub Teaching Hospital, Abbottabad from 1st March 2006 to 28thFebruary 2007. Non-probability convenience sampling was done to select 500 females from thosevisiting Ayub Teaching Hospital Abbottabad as outdoor patients or accompanying person.History, examination, and serum alanine aminotransferase estimation were followed by the initialscreening for Hepatitis B surface Antigen (HBsAg) using immunochromatographic device.Enzyme linked Immunosorbent assay was used to confirm the presence of HBsAg. Results:HBsAg was detected in 3% of the women. History of multiple injections was present in 100%,blood transfusion in 22%, dental procedure in 46% and surgical procedure in 43% of the subjects.Only 1% women had been vaccinated. Conclusion: Seroprevalence of the Hepatitis B is notdifferent from the figures reported by the studies previously conducted on general population inPakistan. However it is different from those reported for the special groups.Keywords. Hepatitis B, Viral Hepatitis, Chronic liver disease, HBsAg, immunochromatographicdevice, ELISA


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