COMPARISON OF AZTREONAM AGAINST OTHER ANTIBIOTICS USED IN URINARY TRACT INFECTIONS
AbstractBackground: Urinary tract infection is a very common problem in adults as well as in children. There is always needfor the right antibiotic to be chosen for treatment. Methods: This study was conducted at Microbiology section inPathology department of Ayub Medical College, Abbottabad, Pakistan. In this study the aztreonam which is onlyeffective against gram negative bacilli has been compared with other conventionally used antibiotics, ampicillin,cotrimoxazole, minocycline, pipemedic acid, nalidixic acid, norfloxacin, ciprofloxacin, gentamicin and ceftriaxone.Results: Total gram negative isolates were 342. Out of this 76.6% (262) were E.coli. Klebsiella pneumoniae 14.3%(49), proteus species 5.2%(I8) and pseudomonas aeruginosa were 3.8% (13). The aztreonam showed 78% sensitivityagainst gram negative bacilli which is better than norfloxacin which showed 62.2% sensitivity.
Finkelstein-R. Kassis-E, Reinhertz-G i al. Communityacquired urinary tract infections in adults: a hospital viewpoint.
J-Hosp-lnfect. 1998 Mar; 38(3): 193-202
Aug-B.S. Urinary tract infections. Singapore Medical Journal,
June; 36(3): 314-7.
Bertram G. Katzung; Ernest Jawetz. Penicillins and
cephalosporins in basic and clinical pharmacology fifth edition
; 626-636. Applarton and Lange; Norwalk. Connecticut.
Sharifi-R; Geckler-R; Childs-S. Treatment of urinary tract
infections; Selecting an appropriate broad-spectrum antibiotic
for nosocomial infections. American Journal of Medicine ,1969;
Grau-S, Monterde-J. Dronie-L & Salvado-M. Management of
urinary tract infections: a comprehensive review. Pharm- WorldSci. 1997 Oct; 19(5): 236-45.
Gruenberg RN & Bettelheim KA. Geographical variation in
serological types of urinary Escherichia Coli. Journal of Medical
Microbiology, 1969; 2: 219.
Ishikawa-K; Suzuki-K; Higa-1. Comparative susceptibility of 10
antimicrobials against pseudomonas Kansenshojakn- Zasshi,
June; 70(6): 584-590.
Turck. M. & W. Stamm Nosocomial infection of urinary tract.
American Journal of Medicine. 1981; 70 651-654.
MacCaig DJ. Stewart D. Harvey Y. Downie S. Scott C’J. An
assessment of antibiotic therapy of urinary tract infections in
elderly hospitalized patients. Health Bulletin Edinburgh. 1995.
Papapctroponlou M, Pagonoponlou O, Konskonni E. Prevalence
and sensitivity to antibiotics of enterobacteriaceae isolated from
urinary cultures in some microbiology laboratories of a city in
Greece. Pathol Biol Paris 1997 Nov; 45(9):7 l6-20
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.